Psychopharmacology Research Unit

The psychopharmacology researches in Gulhane Military Medical Academy (GMMA) has begun in Medical Pharmacology Department in 1984. The researches had been carried on in a laboratory in the basement of the main hospital building till 1996. "Psychopharmacology Research Unit" has been established in GMMA Research Building in 27,03,1997 by the order of Commandership of GMMA (Order number: 0530-39-97-747) as a unit of Medical Pharmacology Department. 

In this unit to make original researches for finding solutions on the recent problems in Neuropsychopharmacology and developing new medicines that can be applied to clinical usage has been aimed.

Experimental researches on:

  • alcohol and substance dependence

  • epilepsy and seizures

  • anxiety and depression

  • neurodegenerative illnesses, Alzheimer's disease and dementia.

  • learning and memory

  • the quantification of neurotransmitters by HPLC and microdialysis

  • acute and chronic pain

For Routine Purposes,

  • Medical Faculty 3rd grade pharmacology course (6 practice hours)

  • GMMA Health Sciences Institute master's and doctorate courses (practice for thesis)

  • Postgraduate courses (theory and practice) for Experimental Psychology Department of University of Hacettepe have been given.

Scientific Production:

Up to now 63 articles have been published in journals indexed by SCI (62 of them are research articles and one of them is a review article) . The contribution of this unit to total scientific production of GMMA is approximately %11.

Click here to reach publications...

There are two laboratories in Psychopharmacology Research Unit. Those laboratories have all the qualifications for behavioral experimental studies on laboratory animals. 
The heat and moisture are kept in limits (22±3°C and %60±5). 12 hours darkness and 12 hours light cycle procedure has been fallowed. In all the experiments performed in this unit the rules of Helsinki Declaration and The Guide for Usage and Care of Laboratory Animals published by American National Institute of Health (NIH) have been strictly fallowed. Swiss-Webster mice and Wistar Rats have been used in experiments.

 

 

 

 

 

Research Equipments:

Open field locomotor activity

Opto varimex minor (Columbus, OH, USA)

Open field locomotor activity (10 cages)

MAY 9905 (Commat Ins., TR)

HPLC (High Pressure Liquid Chromatography)

Agilent 1100A – USA

Stereotaxic frame

ASI Ins., SAS 4100, USA

Shuttle-box

Reflex- 16 (Columbus, USA)

Tail-flick

Type 812 (Columbus, USA)

Rodent shocker

Schock Reizgeret, Type 207(HSE,Germany)

Convulsiometer

Convuls 1,(Columbus, USA)

Drug discrimination test system (8 cages)

Coulbourn Ins, USA

Elevated plus maze

Commat Ins., TR

Hot plate

Commat Ins., TR

Rotorod/Accelerod performance test system

Rotamex V-EE/85 (Columbus, USA)

Acoustic Startle Reflex System

Coulbourn Ins, USA

         

          

 


 

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Last update: 01.12.2006